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Kemeny Optimal Aggregation (KOA)

application in consensus ranking of microRNA targets

Submitted by ChenLiang on Fri, 09/02/2016 - 21:59

MicroRNAs are very recently discovered small noncoding RNAs, responsible for negative regulation of gene expression. Members of this endogenous family of small RNA molecules have been found implicated in many genetic disorders. Each microRNA targets tens to hundreds of genes. Experimental validation of target genes is a time- and cost-intensive procedure. Therefore, prediction of microRNA targets is a very important problem in computational biology.

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